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Immunology and Infectious Disease

Field Description

The Graduate Field of Immunology & Infectious Disease (IID) offers broad training in the areas of innate and adaptive immunity, along with the mechanisms used by pathogens to invade, replicate and spread within human and animal populations. We emphasize the basic principles underlying host-pathogen interactions and the experimental tools required to understand those interactions. We are particularly interested in how pathogens are recognized and eliminated by the host.  This includes the signaling pathways utilized by granulocytes, macrophages, dendritic cells, and B- and T-lymphocytes in the context of infection and autoimmune dysfunction. On the pathogen side, we study a wide variety of disease agents (ranging from viruses to bacteria, protozoal, and worms pathogens) in order to identify the mechanisms they use to establish acute and chronic infection in different host species. As a member of the Biomedical and Biological Sciences Graduate Program (BBS), IID is part of a vibrant graduate community in the Veterinary College.


Contact Information

Website: http://www.vet.cornell.edu/bbs
Email: bbscornell@cornell.edu
Phone: 607 253-3276

S3 009 Schurman Hall, Box 38
Cornell University
Ithaca, NY  14853

Subject and Degrees

Concentrations by Subject

Immunology

  • cellular immunology
  • immunochemistry
  • immunogenetics
  • immunopathology
  • infection and immunity

Faculty

Hector Aguilar-Carreno

  • Campus: Ithaca
  • Concentrations: Immunology: immunopathology; infection and immunity
  • Research Interests: entry, egress, and interactions of enveloped virsus with host cells, with emphasis on emerging paramyxoviruses, vaccine and intiviral strategies

Douglas Francis Antczak

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunogenetics
  • Research Interests: pregnancy immunology; immunogenetics; equine immunology

Judith Ann Appleton

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunochemistry; immunopathology
  • Research Interests: immunity to nematode parasites colonizing mucosal sites

Avery August

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunogenetics; immunopathology; infection and immunity
  • Research Interests: regulation of T-cell activation, development and function; regulation of T-cell differentiation; regulation of mast cell function; regulation of eosinophil

Dwight Douglas Bowman

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: immune response of hosts to parasites; immunodiagnostics; vaccine validation

Margaret S. Bynoe

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunochemistry; immunopathology; infection and immunity
  • Research Interests: cellular immunology; immunochemistry; immunopathology; infection and immunity; molecular basis of antigen-induced immune suppression and the modulation of the innate immune system response in autoimmune diseases and immunity against cancer.

Yung-Fu Chang

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunopathology; infection and immunity
  • Research Interests: vaccine development; adjuvant and vaccine delivery system; immunopathology of infectious disease; molecular basis of bacterial pathogenesis; host defense mechanisms

Pamela V. Chang

  • Campus: Ithaca
  • Concentrations: Immunology: immunochemistry
  • Research Interests: The overall theme of our research is to understand how the host immune system is regulated by the gut microbiota through their secretion of small molecule metabolites. Our research focuses primarily on two areas: (1) the identification of metabolites produced by the gut microbiota that regulate the host immune system and, building on these discoveries, (2) the development of chemical tools to modulate the immune response. We employ biological and chemical approaches including the tools of molecular and cellular immunology, microbiology, chemical biology, chemistry, biochemistry, and cell biology to elucidate key communication pathways between the gut microbiota and the host immune system. Our ultimate goal is to understand how immune homeostasis is maintained in the intestines, as such discoveries would have broad implications for the development of therapeutics and prophylactics for many inflammatory diseases.

Theodore G Clark

  • Campus: Ithaca
  • Concentrations: Immunology: immunogenetics; infection and immunity
  • Research Interests: molecular parasitology; fish immunology

Rodney Reynolds Dietert

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunogenetics
  • Research Interests: genetic regulation of macrophage function; immunotoxicity

Tobias Doerr

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: cell envelope biology of grain-negative pathogens; antibiotic resistance; tolerance and mechanism of action; microbial sress

Gerald E. Duhamel

  • Campus: Ithaca
  • Concentrations: Immunology: immunopathology; infection and immunity
  • Research Interests: mechanisms of infectious diseases with particular emphasis on molecular mechanisms of bacterial infections in animal models of human diseases, primarily understanding host-pathogen relationships

Julia L. Finkelstein

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: Nutritional modulation of immune response; immunity and inflammation; nutritional immunology; anemia of inflammation; micronutrient interventions; one-carbon metabolism; reproductive health; HIV, neglected tropical diseases; global health (active research projects in India and Latin America); epidemiology; infectious disease epidemiology

Maria Julia Bevilaqua Felippe Flaminio

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; infection and immunity
  • Research Interests: cellular and molecular mechanisms involved in B cell response; neonatal immunology and response to vaccination; immunomodulation using biologic response modifiers; cancer immunotherapy; characterization of primary and secondary immunodeficiencies

Jerrie Gavalchin

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunopathology
  • Research Interests: pathogenetic mechanisms in autoimmunity

Robert O. Gilbert

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: theriogenology; bovine health and reproduction; pathogens involved in regulation of immune responses by hormonal or nutritional factors

David Allan Holowka

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunochemistry
  • Research Interests: molecular immunology; biophysical chemistry and cell biology

Eric C. Ledbetter

  • Campus: Ithaca - (Minor Member)
  • Concentrations: Immunology: infection and immunity
  • Research Interests: ocular infectious diseases and non-invasive in vivo imaging techniques of the anterior segment of the eye with a focus on infectious keratitis. In particular, I am interested in canine herpesvirus-1 ocular surface diseases and am actively researching host-pathogen interactions, mechanisms responsible for latent virus reactivation, and novel therapeutic strategies for ocular canine herpesvirus-1 infections.

Cynthia A. Leifer

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: understanding innate immunity from the inside out; toll-like receptors; signaling; dendritic cells; controlling microbial infection

John C. March

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: metabolic and signal engineering; biotechnology; biological engineering

Helene Marquis

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunochemistry; infection and immunity
  • Research Interests: pathogenesis of listeria monocytogenes; listeria-based vaccines; immunomodulatory function of listeria

Saurabh Mehta

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: Global Health (Countries with active research projects: India, Kenya, Uganda, Ecuador, Mexico, and the US); Infectious Disease Epidemiology, particularly HIV, Tuburculosis, and Neglected Tropical Diseases; Nutritional Interventions and Nutritional Modulation of the Immune Response

Daryl Van Nydam

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: immune response to zoonotic infectious diseases in neonates; immune response interaction with energy balance in periparturient mammals.

John Stuart Leslie Parker

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; infection and immunity
  • Research Interests: mechanisms of apoptosis induction by the mammalian reoviruses and regulation; process of infection, entry, and cellular response to feline calicivirus

Colin Ross Parrish

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunogenetics; infection and immunity
  • Research Interests: virus structure, function and evolution using parvovirus and influenza as models for viral emergence and host switching

Brian Rudd

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunogenetics; immunopathology; infection and immunity
  • Research Interests: developmental immunology; host response to infection

David G Russell

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: the biology of intracellular infection, with emphasis on mycobacteria

Luis M. Schang

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: role of cellular protein, lipids, and glycans play in viral infection

Ynte Hein Schukken

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; infection and immunity
  • Research Interests: immune response in pate gestation; immune response to intramammary infections in the bovine

Kenneth William Simpson

  • Campus: Ithaca
  • Concentrations: Immunology: immunopathology; infection and immunity
  • Research Interests: host pathogen interactions in inflammatory bowel disease and helicobacter infection of the gastrointestinal tract

Ankur Singh

  • Campus: Ithaca
  • Concentrations: Immunology: immunopathology; infection and immunity
  • Research Interests: immune-engineering, cancer engineering, lymphoma and hematological malignancies, biomaterials, vaccine and immuno therapy, stem cell engineering, inflammation

Holger Sondermann

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: protein structure and function; bacteria pathogensis; biochemistry and biophysics

Jeongmin Song

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: Bacteria-Host Interaction; Typhoid toxin; Salmonella Typhi Pathogenesis; Animal Model

Elia D. Tait Wojno

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunopathology; infection and immunity
  • Research Interests: Immune responses during helminth infection and allergic disease, focusing on the role of cytokines and prostaglandins in the regulation of innate immune responses at mucosal tissues in multiple species.

Gerlinde Van de Walle

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; infection and immunity
  • Research Interests: alphaherpesvirus pathogenesis; basic biology/immunology of mesenchymal stem cells for regenerative therapy;mammary gland stem cell biology and carcinogenesis

Brian C. VanderVen

  • Campus: Ithaca
  • Concentrations: Immunology: immunochemistry; immunogenetics; immunopathology; infection and immunity
  • Research Interests: Host-pathogen interactions, bacterial physiology, drug discovery, intracellular pathogens

Bettina Wagner

  • Campus: Ithaca
  • Concentrations: Immunology: cellular immunology; immunogenetics; immunopathology; infection and immunity
  • Research Interests: antibody structure and functions; immune mechanisms of allergy; neonatal tolerance; immunogenetics; immune reagents for veterinary species

Gary R Whittaker

  • Campus: Ithaca
  • Concentrations: Immunology: infection and immunity
  • Research Interests: viral pathogenesis; virus-bacteria co-infection